This week, an editorial was published in the Journal of Personalized Medicine, entitled: A Personalized Approach to Evaluating and Treating Autism Spectrum Disorder. This editorial briefly discusses the 21 papers published as part of a Special Edition. Dr. Richard E. Frye is the (chief) Guest Editor of the Special Edition. The three Co-Guest Editors are Drs. Shannon Rose, Daniel A. Rossignol, and Richard G. Boles. Dr. Boles is the Chief Medical & Scientific Officer of NeuroNeeds®, while Drs. Frye and Rossignol are members of the Medical Advisory Committee.  Free access to the editorial, and the 21 papers it discusses, can be found online at  These papers significantly advance the field regarding how personalized medicine approaches (treating the disease in each patient as unique in many ways) have practical applications in diagnosis and treatment.   While effective treatment and management for individuals with ASD is only starting to be uncovered, the authors cite the importance of mitochondria in autism.  “Perhaps most apparent, these articles underline the primacy of mitochondria in ASD, including oxidative stress and redox regulation, which are themselves major functions of mitochondria.” The importance of the immune system in autism is also underscored. Dr Boles poses the question, “Is ASD (autism) itself a result of abnormal mitochondria, with effects on neurons and/or leukocytes—essentially a “Bad Trio” of mitochondrial dysfunction, oxidative stress and redox regulation, and immune system dysfunction.”  For more information about the Mitochondrial Cocktail, SpectrumNeeds®, and/or EnergyNeeds®, please visit or email

Disclosure:  Dr. Boles is the Chief Medical & Scientific Officer for NeuroNeeds LLC, a start-up company that makes dietary supplements designed for individuals coping with wide-range of disorders associated with mitochondrial dysfunction, including many functional (e.g.  chronic fatigue,  pain,  nausea,  dizziness), neuro-developmental (e.g.  autism,  ADHD), and neuropsychiatric (e.g.  anxiety,  depression) conditions.    As always, it is recommended that you contact your healthcare provider regarding all dietary supplements and all other changes to disease management.

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